COoL Lab in last 5 years..

• Joshi, M.P., Uday A., Rajamani, S.(2022) Elucidating N-acyl amino acids as a model protoamphiphilic system. Commun Chem 5, 147 (2022). https://doi.org/10.1038/s42004-022-00762-9

• Sarkar, S., Dagar, S., Lahiri,K., Rajamani, S.(2022), pH-responsive self-assembled compartments as tuneable model protocellular membrane systems. ChemBioChem. https://doi.org/10.1002/cbic.202200371

• Dagar, S., Sarkar, S. and Rajamani, S. (2022), Porphyrin in prebiotic catalysis: Ascertaining a route for the emergence of early metalloporphyrins. ChemBioChem. Accepted Author Manuscript. https://doi.org/10.1002/cbic.202200013

• Joshi, M.P., Steller, L.; Van Kranendonk, M.J.; Rajamani, S. Influence of Metal Ions on Model Protoamphiphilic Vesicular Systems: Insights from Laboratory and Analogue Studies. Life 2021, 11, 1413. https://doi.org/10.3390/life11121413.

• Sarkar, S. Dagar, S., Rajamani, S. (2021) Influence of Wet-dry Cycling on the Self-Assembly and Physicochemical Properties of Model Protocellular Membrane Systems. ChemSystemsChem, 2021. doi.org/10.1002/syst.202100014.

• Joshi, M. P., Sawant, A. A., Rajamani, S (2021). Spontaneous emergence of membrane-forming protoamphiphiles from a lipid-amino acid mixture under wet-dry cycles. Chem. Sci, 2021. DOI: 10.1039/D0SC05650B​

• Sarkar, S., Das, S., Dagar, S., Joshi, M. P., Mungi, C. V., Sawant, A. A., Patki, G.M. & Rajamani, S. Prebiological Membranes and Their Role in the Emergence of Early Cellular Life. J Membrane Biol (2020).

• Dagar, S., Sarkar, S., & Rajamani, S. (2020). Geochemical influences on nonenzymatic oligomerization of prebiotically relevant cyclic nucleotides. RNA, 26(6), 756-769.

• Sarkar, S., Dagar, S., Verma, A., & Rajamani, S. (2020). Compositional heterogeneity confers selective advantage to model protocellular membranes during the origins of cellular life. Scientific reports, 10(1), 1-11.

• Bapat, N. V., Paithankar, H., Chugh, J., & Rajamani, S. (2020). NMR analysis of nucleotide π-stacking in prebiotically relevant crowded environment. Communications Chemistry, 3(1), 1-6.

• Roy, S., Bapat, N. V., Derr, J., Rajamani, S., & Sengupta, S. Emergence of ribozyme and tRNA-like structures from mineral-rich muddy pools on prebiotic earth. Journal of Theoretical Biology (2020).

• Mungi, C. V., Bapat, N. V., Hongo, Y., & Rajamani, S. (2019). Formation of Abasic Oligomers in Nonenzymatic Polymerization of Canonical Nucleotides. Life, 9(3), 57.

• Pandey, S., Clarke, J., Nema, P., Bonaccorsi, R., Som, S., Sharma, M., ... & Vaishampayan, P. (2019). Ladakh: diverse, high-altitude extreme environments for off-earth analogue and astrobiology research. International Journal of Astrobiology, 1-21.

• Bapat, N. V., & Rajamani, S. (2018). Templated replication (or lack thereof) under prebiotically pertinent conditions. Scientific reports, 8(1), 15032.​

• Joshi M. P., Samanta A., Tripathy G. R. and Rajamani S. (2017). Formation and Stability of Prebiotically Relevant Vesicular Systems in Terrestrial Geothermal Environments, Life, 7(4), 51.​

COoL Lab Early days

• Mungi, C. V, Singh, S.K., Chugh, J., and Rajamani, S. (2016). Synthesis of barbituric acid containing nucleotides and their implications for the origin of primitive informational polymers. Phys. Chem. Chem. Phys. 18, 20144–20152.

• Xulvi-Brunet, R., Campbell, G.W., Rajamani, S., Jiménez, J.I., and Chen, I.A. (2016). Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments. Methods 106, 86–96.​

• Bapat, N. V, and Rajamani, S. (2015). Effect of Co-solutes on Template-Directed Nonenzymatic Replication of Nucleic Acids. J. Mol. Evol. 81, 72–80.

• Mungi, C. V, and Rajamani, S. (2015). Characterization of RNA-Like Oligomers from Lipid-Assisted Nonenzymatic Synthesis: Implications for Origin of Informational Molecules on Early Earth. Life, 5, 65–84.

• Scharf Caleb, Virgo Nathaniel, Cleaves H. James II, Aono Masashi, Aubert-Kato Nathanael, Aydinoglu Arsev, Barahona Ana, Barge Laura M., Benner Steven A., Biehl Martin, Brasser Ramon, Butch Christopher J., Chandru Kuhan, Cronin Leroy, Danielache Sebastian, Fischer Jakob, Hernlund John, Hut Piet, Ikegami Takashi, Kimura Jun, Kobayashi Kensei, Mariscal Carlos, McGlynn Shawn, Menard Brice, Packard Norman, Pascal Robert, Pereto Juli, Rajamani Sudha, Sinapayen Lana, Smith Eric, Switzer Christopher, Takai Ken, Tian Feng, Ueno Yuichiro, Voytek Mary, Witkowski Olaf, and Yabuta Hikaru. (2015) A Strategy for Origins of Life Research. Astrobiology., 15(12), 1031-1042.

Pre-COoL Lab​

• Ivica, N. A., Obermayer, B., Campbell, G. W., Rajamani, S., Gerland, U., & Chen, I. A. (2013). The paradox of dual roles in the RNA world: resolving the conflict between stable folding and templating ability. Journal of molecular evolution, 77(3), 55-63.​

• Derr, J., Manapat, M. L., Rajamani, S., Leu, K., Xulvi-Brunet, R., Joseph, I., ... & Chen, I. A. (2012). Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences. Nucleic acids research, 40(10), 4711-4722.​

• Leu, K., Obermayer, B., Rajamani, S., Gerland, U., & Chen, I. A. (2011). The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA. Nucleic acids research, 39(18), 8135-8147.​

• Rajamani, S., Ichida, J. K., Antal, T., Treco, D. A., Leu, K., Nowak, M. A., ... & Chen, I. A. (2010). Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication. Journal of the American Chemical Society, 132(16), 5880-5885.​

• Rajamani, S., Vlassov, A., Benner, S., Coombs, A., Olasagasti, F., & Deamer, D. (2008). Lipid-assisted synthesis of RNA-like polymers from mononucleotides. Origins of Life and Evolution of Biospheres, 38(1), 57-74.​

• Zepik, H.H., Rajamani, S., Maurel, M.-C., and Deamer, D. (2007). Oligomerization of thioglutamic acid: encapsulated reactions and lipid catalysis. Orig. Life Evol. Biosph. 37, 495–505.​

• Deamer, D., Singaram, S., Rajamani, S., Kompanichenko, V., and Guggenheim, S. (2006). Self-assembly processes in the prebiotic environment. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 361, 1809–1818.​​

• Li, J., Zhu, M., Rajamani, S., Uversky, V.N., and Fink, A.L. (2004). Rifampicin Inhibits α-Synuclein Fibrillation and Disaggregates Fibrils. Chem. Biol. 11, 1513–1521.

• Sudha, R., Anantharaman, L., Sivaram, M.V.S., Mirsamadi, N., Choudhury, D., Lohiya, N.K., Gupta,  R.B., and Roy, R.P. (2004). Linkage of Interactions in Sickle Hemoglobin Fiber Assembly: INHIBITORY EFFECT EMANATING FROM MUTATIONS IN THE AB REGION OF THE α-CHAIN IS ANNULLED BY A MUTATION AT ITS EF CORNER . J. Biol. Chem. 279, 20018–20027.​

• Sivaram, M.V.S., Sudha, R., and Roy, R.P. (2001). A Role for the α113 (GH1) Amino Acid Residue in the Polymerization of Sickle Hemoglobin: EVALUATION OF ITS INHIBITORY STRENGTH AND INTERACTION LINKAGE WITH TWO FIBER CONTACT SITES (α16/23) LOCATED IN THE AB REGION OF THE α-CHAIN . J. Biol. Chem. 276, 18209–18215.